About the Labratory:
|University of the Negev, Beer Sheba, Israel
University of North Carolina, Chapel Hill, USA
My research interests are in molecular/genetic cancer epidemiology, cancer prevention and screening and in molecular or personalized targeted medicine. A particular area of focus of my work has been the interaction between behavioral / environmental risk factors for cancer, and between genetic events (mutations, polymorphisms, variants, gene-expression) in the causation of breast, colorectal, lung, gynecological, pancreato-hepato-biliary and other cancers. Cancer chemoprevention studies are another focus of my scientific work. In addition, I am studying and coordinating the cancer screening activities on a national level in Israel (from policy to implementation-adherence, quality and outcomes), and studying unique founder mutations leading to cancer through the Familial Cancer Consultation Service which cares for thousands of mutation carriers. My work involves a deep epidemiological evaluation of more than 40,000 study participants combined with massive genetic testing using RT-PCR, Sanger sequencing, deep next-generation sequencing, microarray testing, multi-gene expression panels studies, Onco-chip multi-SNP panel, whole exome analysis and other laboratory techniques.